Everything about Ribonucleoprotein totally explained
Ribonucleoprotein (RNP) is a
nucleoprotein that contains
RNA, for example it's a compound that combines
ribonucleic acid and
protein together. It is one of the main components of
nucleolus.
RNP is an RNA binding
motif in an RNA binding protein.
Aromatic amino acid residues in this RNP motif result in stacking interactions with RNA.
Lysine residues in the
helical portion of RNA binding proteins help to stabilize interactions with nucleic acids. This nucleic acid binding is a result of highly positive nature of lysine
side chains and the negative character of
nucleic acid phosphate backbones.
Anti-RNP antibodies are linked to
mixed connective tissue disease although nearly 40% of
Lupus erythematosus patients will be positive for anti-RNP. Also Anti-RNP are closely related to sjogren Syndrome and has two types : SS-A (Ro) and SS-B (La).
RNPs play an important role in
Influenzavirus A replication. The
viral RNA is
transcribed into
mRNAs by the
RNA polymerase attached to the RNPs.
List of RNPs
This is a (partial) list of ribonucleoprotein families:
Further Information
Get more info on 'Ribonucleoprotein'.
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